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Article

A nonautonomous role for retinal frizzled-5 in regulating hyaloid vitreous vasculature development.

Investigative ophthalmology & visual science - 1 Dec 2008

Zhang Jianmin, Fuhrmann Sabine, Vetter Monica L

Abstract excerpt

PURPOSE: Frizzled-5 (Fzd5) is expressed in the developing retina of multiple species and appears to play species-specific roles during eye development. The present study analyzed the effects of tissue-specific deletion of Fzd5 on mammalian eye development. METHODS: To generate Fzd5 conditional knockout (CKO) mice, Fzd5(+/-) mice carrying the Six3-Cre transgene were crossed with Fzd5(LoxP/LoxP) mice. To determine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18791178
DOI: 10.1167/iovs.08-2226
PMCID: PMC2679971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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