Article
Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis.
Development (Cambridge, England) - 1 Apr 2014
Korn Claudia, Scholz Beate, Hu Junhao, Srivastava Kshitij, Wojtarowicz Jessica, Arnsperger Tabea, Adams Ralf H, Boutros Michael, Augustin Hellmut G, Augustin Iris
Abstract excerpt
Multiple cell types involved in the regulation of angiogenesis express Wnt ligands. Although β-catenin dependent and independent Wnt signaling pathways have been shown to control angiogenesis, the contribution of individual cell types to activate these downstream pathways in endothelial cells (ECs) during blood vessel formation is still elusive. To investigate the role of ECs in contributing Wnt ligands for...
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