Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of FKBP5 polymorphisms and resting-state activity in a frontotemporal-parietal network.

Translational psychiatry - 18 Oct 2016

Bryant R A, Felmingham K L, Liddell B, Das P, Malhi G S

Abstract excerpt

The FKBP5 polymorphism is a key regulator of the glucocorticoid system underpinning stress responsivity, and risk alleles can increase vulnerability for developing posttraumatic stress disorder. To delineate the specific role of FKBP5 risk alleles unencumbered by the confounds of psychopathology, this study investigated whether high-risk alleles of the FKBP5 polymorphism are characterized by distinctive neural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arousal
Share to Hypothalamo-Hypophyseal System
Share to Nerve Net

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Parietal Lobe

Share to Pituitary-Adrenal System

Share to Stress Disorders, Post-Traumatic

Share to Tacrolimus Binding Proteins

Share to Temporal Lobe

Source

Open in PubMed Open full text

Identifiers

PMID: 27754486
DOI: 10.1038/tp.2016.149
PMCID: PMC5315540

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of FKBP5 polymorphisms and resting-state activity in a frontotemporal-parietal network.PMID 27754486Read ↗

FKBP5 haplotypes and PTSD modulate the resting-state brain activity in Han Chinese adults who lost their only child.Semantic proximity Read ↗

The rs1360780 Variant of FKBP5: Genetic Variation, Epigenetic Regulation, and Behavioral PhenotypesSemantic proximity Read ↗

Role of FKBP5 in emotion processing: results on amygdala activity, connectivity and volume.Semantic proximity Read ↗

Interaction of FKBP5 variant rs3800373 and city living alters the neural stress response in the anterior cingulate cortex.Semantic proximity Read ↗

Epigenetic Changes of FKBP5 as a Link Connecting Genetic and Environmental Risk Factors with Structural and Functional Brain Changes in Major Depression.Semantic proximity Read ↗

The interaction of child abuse and rs1360780 of the FKBP5 gene is associated with amygdala resting-state functional connectivity in young adults.Semantic proximity Read ↗

FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity.Semantic proximity Read ↗

STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5.Semantic proximity Read ↗

FKBP5 polymorphisms induce differential glucocorticoid responsiveness in primary CNS cells - First insights from novel humanized mice.Semantic proximity Read ↗

FKBP5 risk alleles and the development of intrusive memories.Semantic proximity Read ↗

Effect of the common functional FKBP5 variant (rs1360780) on the hypothalamic-pituitary-adrenal axis and peripheral blood gene expression.Semantic proximity Read ↗

Hippocampal volume, FKBP5 genetic risk alleles, and childhood trauma interact to increase vulnerability to chronic multisite musculoskeletal pain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.