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Article

Interaction of FKBP5 variant rs3800373 and city living alters the neural stress response in the anterior cingulate cortex.

Stress (Amsterdam, Netherlands) - 1 Jul 2021

Richter Anja, Al-Bayati Mohammad, Paraskevopoulou Foteini, Krämer Bernd, Pruessner Jens C, Binder Elisabeth B, Gruber Oliver

Abstract excerpt

Psychosocial stress effects of urban living are associated with substantially increased risk for schizophrenia, mood and anxiety disorders, by altering stress-induced activity in the amygdala and pregenual anterior cingulate cortex (ACC). Genetic factors are likely to modulate the impact of city living on stress processing. Growing evidence suggests a key role of FKBP5, a co-chaperone regulating the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33541187
DOI: 10.1080/10253890.2020.1855420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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