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Article

FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity.

Genes, brain, and behavior - 1 Oct 2012

White M G, Bogdan R, Fisher P M, Muñoz K E, Williamson D E, Hariri A R

Abstract excerpt

Individual variation in physiological responsiveness to stress mediates risk for mental illness and is influenced by both experiential and genetic factors. Common polymorphisms in the human gene for FK506 binding protein 5 (FKBP5), which is involved in transcriptional regulation of the hypothalamic-pituitary-adrenal (HPA) axis, have been shown to interact with childhood abuse and trauma to predict stress-related...

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Identifiers

PMID: 22979952
DOI: 10.1111/j.1601-183X.2012.00837.x
PMCID: PMC3838302

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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