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Article

Tissue Specificity of Human Disease Module.

Scientific reports - 17 Oct 2016

Kitsak Maksim, Sharma Amitabh, Menche Jörg, Guney Emre, Ghiassian Susan Dina, Loscalzo Joseph, Barabási Albert-László

Abstract excerpt

Genes carrying mutations associated with genetic diseases are present in all human cells; yet, clinical manifestations of genetic diseases are usually highly tissue-specific. Although some disease genes are expressed only in selected tissues, the expression patterns of disease genes alone cannot explain the observed tissue specificity of human diseases. Here we hypothesize that for a disease to manifest itself in...

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Identifiers

PMID: 27748412
DOI: 10.1038/srep35241
PMCID: PMC5066219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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