Article

Understanding Tissue-specific Gene Regulation

2017-02-21

Abstract excerpt

Although all human tissues carry out common processes, tissues are distinguished by gene expres-sion patterns, implying that distinct regulatory programs control tissue-specificity. In this study, we investigate gene expression and regulation across 38 tissues profiled in the Genotype-Tissue Expression project. We find that network edges (transcription factor to target gene connections) have higher tissue-specific...

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Literature Corpus work: 570eb328-57c7-5627-87fb-b3f9964fbdf5
DOI: 10.1101/110601

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