Article
Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.
BMC medical genetics - 28 May 2010
Han Xueyao, Luo Yingying, Ren Qian, Zhang Xiuying, Wang Fang, Sun Xiuqin, Zhou Xianghai, Ji Linong
Abstract excerpt
BACKGROUND: Recently, several genome-wide and candidate gene association studies have identified many novel genetic loci for type 2 diabetes (T2D); among these genes, CDKAL1, IGF2BP2, SLC30A8, CDKN2A/B, HHEX, FTO, TCF2, KCNQ1, and WFS1 are the most important. We aimed to determine the effects of these genetic loci associated with T2D in the Chinese Han population of China. METHODS: Single-nucleotide polymorphisms...
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