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Whole Exome Sequencing Study in a Family with Type 2 Diabetes Mellitus

1 Nov 2021

Abstract excerpt

Background: Type 2 diabetes mellitus (T2DM) is characterized by β cell decline in the pancreas and insulin resistance. This study aimed to investigate the possible pathogenic gene mutation sites of T2DM patients using whole exome sequencing. Materials and Methods: We recruited a Chinese family with 3-generation history of diabetes. The whole blood genomic DNA of seven members of the family was extracted and sent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34815695
DOI: 10.2147/ijgm.s335090

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