Article
Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore.
The Journal of clinical endocrinology and metabolism - 1 Jan 2010
Tan Jonathan T, Ng Daniel P K, Nurbaya Siti, Ye Sandra, Lim Xiu Li, Leong Helen, Seet Lin Tze, Siew Wei Fong, Kon Winston, Wong Tien Yin, Saw Seang Mei, Aung Tin, Chia Kee Seng, Lee Jeannette, Chew Suok Kai, Seielstad Mark, Tai E Shyong
Abstract excerpt
CONTEXT: Novel type 2 diabetes mellitus (T2DM) susceptibility loci, identified through genome-wide association studies (GWAS), have been replicated in many European and Japanese populations. However, the association in other East Asian populations is less well characterized. OBJECTIVE: To examine the effects of SNPs in CDKAL1, CDKN2A/B, IGF2BP2, HHEX, SLC30A8, PKN2, LOC387761, and KCNQ1 on risk of T2DM in...
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