Article

Loss-of-Function <i>FLNC</i> Variants are Associated with Arrhythmogenic Cardiomyopathy Phenotypes when Identified through Exome Sequencing of a General Clinical Population

2021-10-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The FLNC gene has recently garnered attention as a likely cause of arrhythmogenic cardiomyopathy (ACM), which is considered an actionable genetic condition. However, the association with disease in an unselected clinical population is unknown. We hypothesized that individuals with loss-of-function variants in FLNC ( FLNC LOF ) would have increased odds for ACM-associated pheno...

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Literature Corpus work: a8be3ffd-7cdc-5a7d-a65f-9470c6655e79
DOI: 10.1101/2021.10.28.21265491

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Loss-of-Function <i>FLNC</i> Variants are Associated with Arrhythmogenic Cardiomyopathy Phenotypes when Identified through Exome Sequencing of a General Clinical PopulationDOI 10.1101/2021.10.28.21265491Read

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