Article
Ultra-Deep Sequencing Characterization of HCV Samples with Equivocal Typing Results Determined with a Commercial Assay.
International journal of molecular sciences - 7 Oct 2016
Minosse Claudia, Giombini Emanuela, Bartolini Barbara, Capobianchi Maria R, Garbuglia Anna R
Abstract excerpt
Hepatitis C virus (HCV) is classified into seven phylogenetically distinct genotypes, which are further subdivided into related subtypes. Accurate assignment of genotype/subtype is mandatory in the era of directly acting antivirals. Several molecular methods are available for HCV genotyping; however, a relevant number of samples with indeterminate, mixed, or unspecified subtype results, or even with misclassified...
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