Article
Prevalence of mixed genotype hepatitis C virus infections in the UK as determined by genotype-specific PCR and deep sequencing.
Journal of viral hepatitis - 1 May 2018
McNaughton A L, Sreenu V B, Wilkie G, Gunson R, Templeton K, Leitch E C M
Abstract excerpt
The incidence of mixed genotype hepatitis C virus (HCV) infections in the UK is largely unknown. As the efficacy of direct-acting antivirals is variable across different genotypes, treatment regimens are tailored to the infecting genotype, which may pose issues for the treatment of underlying genotypes within undiagnosed mixed genotype HCV infections. There is therefore a need to accurately diagnose mixed...
Topics
- Adult
- Cohort Studies
- Coinfection
- Female
- Genotype
- Genotyping Techniques
- Hepacivirus
- Hepatitis C
- High-Throughput Nucleotide Sequencing
- Humans
- Male