Article
Evaluation of the Abbott RealTime HCV genotype II plus RUO (PLUS) assay with reference to core and NS5B sequencing.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2017
Mallory Melanie A, Lucic Danijela, Ebbert Mark T W, Cloherty Gavin A, Toolsie Dan, Hillyard David R
Abstract excerpt
BACKGROUND: HCV genotyping remains a critical tool for guiding initiation of therapy and selecting the most appropriate treatment regimen. Current commercial genotyping assays may have difficulty identifying 1a, 1b and genotype 6. OBJECTIVE: To evaluate the concordance for identifying 1a, 1b, and genotype 6 between two methods: the PLUS assay and core/NS5B sequencing. STUDY DESIGN: This study included 236 plasma...
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