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Article

A novel standardized deep sequencing-based assay for hepatitis C virus genotype determination.

Scientific reports - 8 Mar 2018

Rodriguez Christophe, Soulier Alexandre, Demontant Vanessa, Poiteau Lila, Mercier-Darty Mélanie, Bouvier-Alias Magali, Pawlotsky Jean-Michel, Chevaliez Stéphane

Abstract excerpt

Hepatitis C virus (HCV) genotype and subtype (1a/1b) identification is needed to tailor anti-HCV therapy. Currently available methods accurately identify the genotype and differentiate subtypes 1a from 1b. However, these assays have not been designed to identify other HCV subtypes, nor to recognize mixed genotype/subtype infections, emphasizing the need for a high-resolution system based on phylogenetic analysis...

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Source

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Identifiers

PMID: 29520035
DOI: 10.1038/s41598-018-22614-0
PMCID: PMC5843601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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