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Article

Variation in human recombination rates and its genetic determinants.

PloS one - 1 Jan 2011

Fledel-Alon Adi, Leffler Ellen Miranda, Guan Yongtao, Stephens Matthew, Coop Graham, Przeworski Molly

Abstract excerpt

BACKGROUND: Despite the fundamental role of crossing-over in the pairing and segregation of chromosomes during human meiosis, the rates and placements of events vary markedly among individuals. Characterizing this variation and identifying its determinants are essential steps in our understanding of the human recombination process and its evolution. STUDY DESIGN/RESULTS: Using three large sets of...

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Identifiers

PMID: 21698098
DOI: 10.1371/journal.pone.0020321
PMCID: PMC3117798

Genes

PRDM9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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