Article
Charcot-Marie-Tooth gene, SBF2, associated with taxane-induced peripheral neuropathy in African Americans.
Oncotarget - 13 Dec 2016
Schneider Bryan P, Lai Dongbing, Shen Fei, Jiang Guanglong, Radovich Milan, Li Lang, Gardner Laura, Miller Kathy D, O'Neill Anne, Sparano Joseph A, Xue Gloria, Foroud Tatiana, Sledge George W
Abstract excerpt
PURPOSE: Taxane-induced peripheral neuropathy (TIPN) is one of the most important survivorship issues for cancer patients. African Americans (AA) have previously been shown to have an increased risk for this toxicity. Germline predictive biomarkers were evaluated to help identify a priori which patients might be at extraordinarily high risk for this toxicity. EXPERIMENTAL DESIGN: Whole exome sequencing was...
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