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Article

Pharmacogenetics of taxane-induced neurotoxicity in breast cancer: Systematic review and meta-analysis.

Clinical and translational science - 1 Oct 2022

Guijosa Alberto, Freyria Ana, Espinosa-Fernandez Jose Rodrigo, Estrada-Mena Francisco J, Armenta-Quiroga Ana Sofía, Ortega-Treviño Maria Fernanda, Catalán Rodrigo, Antonio-Aguirre Bani, Villarreal-Garza Cynthia, Perez-Ortiz Andric C

Abstract excerpt

Taxane-based chemotherapy regimens are used as first-line treatment for breast cancer. Neurotoxicity, mainly taxane-induced peripheral neuropathy (TIPN), remains the most important dose-limiting adverse event. Multiple genes may be associated with TIPN; however, the strength and direction of the association remain unclear. For this reason, we systematically reviewed observational studies of TIPN pharmacogenetic...

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Identifiers

PMID: 35892315
DOI: 10.1111/cts.13370
PMCID: PMC9579387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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