Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations within the promotor region of the human histamine H4 receptor gene in psoriasis patients.

Pharmacological research - 1 Dec 2016

Mommert Susanne, Ratz Lisanne, Herwig Kira, Rost Maren, Gutzmer Ralf, Werfel Thomas

Abstract excerpt

Environmental triggers and genetic factors are supposed to lead to complex gene expression changes in psoriasis and interact in the manifestation of the disease. The histamine H4 receptor (HRH4) is functionally expressed on Th17 cells and plasmacytoid dendritic cells (pDCs) which play a prominent role in the pathogenesis of psoriasis. On pDCs a higher basal expression level of the HRH4 in psoriasis patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Genotype
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Psoriasis

Source

Identifiers

PMID: 27725312
DOI: 10.1016/j.phrs.2016.10.003

Genes

HRH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations within the promotor region of the human histamine H4 receptor gene in psoriasis patients.PMID 27725312Read ↗

Polymorphisms in human histamine receptor H4 gene are associated with atopic dermatitis.Semantic proximity Read ↗

Histamine pharmacogenomics.Semantic proximity Read ↗

Polymorphisms of human histamine receptor H4 gene are associated with breast cancer in Chinese Han population.Semantic proximity Read ↗

Variability in histamine receptor genes HRH1, HRH2 and HRH4 in patients with hypersensitivity to NSAIDs.Semantic proximity Read ↗

Influence of HRH2 promoter polymorphism on aberrant DNA methylation of DAPK and CDH1 in the gastric epithelium.Semantic proximity Read ↗

Unlocking the role of the B7-H4 polymorphism in psoriasis: Insights into methotrexate treatment outcomes: A prospective cohort study.Semantic proximity Read ↗

Genetic variation within the histamine pathway among patients with asthma--a pilot study.Semantic proximity Read ↗

Genetic variability of histamine receptors in patients with Parkinson's disease.Semantic proximity Read ↗

The role of histamine H 4 receptor in immune and inflammatory disordersSemantic proximity Read ↗

Association between copy-number variations of the human histamine H4 receptor gene and atopic dermatitis in a Chinese population.Semantic proximity Read ↗

Histamine H4 receptor gene polymorphisms: a potential predictor of oral H1 antihistamine efficacy for allergic rhinitis.Semantic proximity Read ↗

Associations of polymorphisms in histidine decarboxylase, histamine N-methyltransferase and histamine receptor H3 genes with breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.