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Article

Associations of polymorphisms in histidine decarboxylase, histamine N-methyltransferase and histamine receptor H3 genes with breast cancer.

PloS one - 1 Jan 2014

He Gong-Hao, Lin Jia-Ji, Cai Wen-Ke, Xu Wen-Mang, Yu Zheng-Ping, Yin Sun-Jun, Zhao Can-Hu, Xu Gui-Li

Abstract excerpt

We previously found that genetic polymorphisms in gene coding for histamine H4 receptors were related to the risk and malignant degree of breast cancer. The roles of polymorphisms in other histamine-related genes, such as histidine decarboxylase (HDC), histamine N-methyltransferase (HNMT) and histamine H3 receptor (HRH3), remain unexplored. The aim of this study is to analyze the clinical associations of...

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Source

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Identifiers

PMID: 24835231
DOI: 10.1371/journal.pone.0097728
PMCID: PMC4023951

Genes

HDC
HNMT
HRH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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