Article
Polymorphisms in human histamine receptor H4 gene are associated with atopic dermatitis.
The British journal of dermatology - 1 May 2010
Yu B, Shao Y, Zhang J, Dong X L, Liu W L, Yang H, Liu L, Li M H, Yue C F, Fang Z Y, Zhang C, Hu X P, Chen B C, Wu Q, Chen Y W, Zhang W, Wan J
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a chronic skin disease affecting more than 15% of children and 2% of adults. A strong connection between genetic factors and AD has been described for a long time. Histamine receptor H4 (HRH4) has been shown to be related to different kinds of allergic and autoimmune disorders. However, an association between HRH4 and AD has not yet been reported. OBJECTIVES: To examine a...
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