Article
Association between copy-number variations of the human histamine H4 receptor gene and atopic dermatitis in a Chinese population.
Clinical and experimental dermatology - 1 Apr 2013
Chen B, Ye T, Shao Y, Zhang J, Zhong Q, Hu X, Zhang W, Yu B
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a chronic, relapsing allergic skin disease. The histamine H4 receptor (HRH4) has been shown to be associated with a number of autoimmune disorders, including AD. AIM: To explore a possible association between copy-number variations (CNVs) of the HRH4 gene and the risk of AD in a Chinese population. METHODS: Genomic DNA and RNA were collected from 541 patients with AD and 613...
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