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Article

Variability in histamine receptor genes HRH1, HRH2 and HRH4 in patients with hypersensitivity to NSAIDs.

Pharmacogenomics - 1 Nov 2013

Ayuso Pedro, Blanca Miguel, Cornejo-García José A, Torres María José, Doña Inmaculada, Salas María, Blanca-López Natalia, Canto Gabriela, Rondón Carmen, Campo Paloma, Laguna José J, Fernández Javier, Martínez Carmen, Agúndez José Ag, García-Martín Elena

Abstract excerpt

AIM: Histamine plays an important role in the pathogenesis of allergic diseases. Genetic variations in histamine receptors (HRH) may influence the expression of allergic diseases. This study analyzes the association between HRH variants and NSAID hypersensitivity reactions. PATIENTS & METHODS: The authors analyzed copy number variations (CNVs) and common functional SNPs in genes HRH1, HRH2 and HRH4 in 442...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24236486
DOI: 10.2217/pgs.13.155

Genes

HRH1
HRH2
HRH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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