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Article

Direct Evidence for P2Y2 Receptor Involvement in Vascular Response to Injury.

Journal of vascular research - 1 Jan 2016

Agca Yuksel, Qian Shaomin, Agca Cansu, Seye Cheikh I

Abstract excerpt

OBJECTIVES: Extracellular nucleotide release at the site of arterial injury mediates the proliferation and migration of vascular smooth muscle cells. Our aim was to investigate the role of the P2Y2 nucleotide receptor (P2Y2R) in neointimal hyperplasia. Approach and Results: Vascular injury was induced by the implantation of a polyethylene cuff around the femoral artery in wild-type and P2Y2R-deficient mice...

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Share to Chemotaxis, Leukocyte
Share to Constriction, Pathologic
Share to Femoral Artery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperplasia

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Neointima

Share to Rats, Transgenic

Source

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Identifiers

PMID: 27723650
DOI: 10.1159/000449059
PMCID: PMC5154871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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