Article
Importance of monocyte chemoattractant protein-1 pathway in neointimal hyperplasia after periarterial injury in mice and monkeys.
Circulation research - 14 Jun 2002
Egashira Kensuke, Zhao Qingwei, Kataoka Chu, Ohtani Kishou, Usui Makoto, Charo Israel F, Nishida Ken-Ichi, Inoue Shujiro, Katoh Makoto, Ichiki Toshihiro, Takeshita Akira
Abstract excerpt
Neointimal hyperplasia is a major cause of restenosis after coronary intervention. Because vascular injury is now recognized to involve an inflammatory response, monocyte chemoattractant protein-1 (MCP-1) might be involved in underlying mechanisms of restenosis. In the present study, we demonstrate the important role of MCP-1 in neointimal hyperplasia after cuff-induced arterial injury. In the first set of...
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