Article
The transcription factor, Nuclear factor, erythroid 2 (Nfe2), is a regulator of the oxidative stress response during Danio rerio development.
Aquatic toxicology (Amsterdam, Netherlands) - 1 Nov 2016
Williams Larissa M, Lago Briony A, McArthur Andrew G, Raphenya Amogelang R, Pray Nicholas, Saleem Nabil, Salas Sophia, Paulson Katherine, Mangar Roshni S, Liu Yang, Vo Andy H, Shavit Jordan A
Abstract excerpt
Development is a complex and well-defined process characterized by rapid cell proliferation and apoptosis. At this stage in life, a developmentally young organism is more sensitive to toxicants as compared to an adult. In response to pro-oxidant exposure, members of the Cap'n'Collar (CNC) basic leucine zipper (b-ZIP) transcription factor family (including Nfe2 and Nfe2-related factors, Nrfs) activate the...
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