Article
From multiallele fish to nonstandard environments, how ZFIN assigns phenotypes, human disease models, and gene expression annotations to genes.
Genetics - 4 May 2023
Bradford Yvonne M, Van Slyke Ceri E, Howe Douglas G, Fashena David, Frazer Ken, Martin Ryan, Paddock Holly, Pich Christian, Ramachandran Sridhar, Ruzicka Leyla, Singer Amy, Taylor Ryan, Tseng Wei-Chia, Westerfield Monte
Abstract excerpt
Danio rerio is a model organism used to investigate vertebrate development. Manipulation of the zebrafish genome and resultant gene products by mutation or targeted knockdown has made the zebrafish a good system for investigating gene function, providing a resource to investigate genetic contributors to phenotype and human disease. Phenotypic outcomes can be the result of gene mutation, targeted knockdown of gene...
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