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Article

Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae.

Cell cycle (Georgetown, Tex.) - 16 Nov 2016

Matrone Gianfranco, Mullins John J, Tucker Carl S, Denvir Martin A

Abstract excerpt

CDK9 is a known regulator of cellular transcription, growth and proliferation. Small molecule inhibitors are currently being developed and assessed in clinical trials as anti-cancer drugs. The zebrafish embryo provides an ideal model to explore the effects of CDK9 inhibition in-vivo. This has not been adequately explored previously at the level of a whole organism. We have compared and contrasted the effects of...

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Identifiers

PMID: 27715402
DOI: 10.1080/15384101.2016.1231283
PMCID: PMC5134698

Genes

CDK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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