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Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development

2019-02-17

Abstract excerpt

<h4>Background</h4> Defects in embryonic development of the thyroid gland are a major cause for congenital hypothyroidism in human newborns but the underlying molecular mechanisms are still poorly understood. Organ development relies on a tightly regulated interplay between extrinsic signaling cues and cell intrinsic factors. At present, however, there is limited knowledge about the specific extrinsic signaling c...

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Literature Corpus work
522d5fff-e7f8-54d6-b253-5bac187fe0b3
DOI
10.1101/551861
Open publication

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Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid DevelopmentDOI 10.1101/551861
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