Article

Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform

2023-06-30

Abstract excerpt

Drug repurposing is an important strategy in COVID-19 treatment, but many clinically approved compounds have not been extensively studied in the context of embryogenesis, thus limiting their administration during pregnancy. Here we used the zebrafish embryo model organism to test the effects of 162 marketed drugs on cardiovascular development. Among the compounds used in the clinic for COVD-19 treatment, we found...

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Literature Corpus work: 16bdcef6-d281-5191-9150-e58cb72c2bd6
DOI: 10.1101/2023.06.29.547094

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