Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular dynamics studies on the DNA-binding process of ERG.

Molecular bioSystems - 15 Nov 2016

Beuerle Matthias G, Dufton Neil P, Randi Anna M, Gould Ian R

Abstract excerpt

The ETS family of transcription factors regulate gene targets by binding to a core GGAA DNA-sequence. The ETS factor ERG is required for homeostasis and lineage-specific functions in endothelial cells, some subset of haemopoietic cells and chondrocytes; its ectopic expression is linked to oncogenesis in multiple tissues. To date details of the DNA-binding process of ERG including DNA-sequence recognition outside...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to DNA-Binding Proteins
Share to Hydrogen Bonding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Conformation

Share to Molecular Docking Simulation

Share to Molecular Dynamics Simulation

Share to Protein Interaction Domains and Motifs

Share to Transcriptional Regulator ERG

Source

Identifiers

PMID: 27714012
DOI: 10.1039/c6mb00506c

Genes

ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular dynamics studies on the DNA-binding process of ERG.PMID 27714012Read ↗

Allosteric Autoinhibition Pathway in Transcription Factor ERG: Dynamics Network and Mutant Experimental Evaluations.Semantic proximity Read ↗

Role of promoter DNA sequence variations on the binding of EGR1 transcription factor.Semantic proximity Read ↗

Molecular dynamics studies of the STAT3 homodimer:DNA complex: relationships between STAT3 mutations and protein-DNA recognition.Semantic proximity Read ↗

Energetic contribution of residues in the Runx1 Runt domain to DNA binding.Semantic proximity Read ↗

Exploring the mechanism of a regulatory SNP of KLK3 by molecular dynamics simulation.Semantic proximity Read ↗

Molecular dynamics simulations demonstrate the regulation of DNA-DNA attraction by H4 histone tail acetylations and mutations.Semantic proximity Read ↗

Experimentally based contact energies decode interactions responsible for protein-DNA affinity and the role of molecular waters at the binding interface.Semantic proximity Read ↗

Structural modeling and molecular simulation analysis of HvAP2/EREBP from barley.Semantic proximity Read ↗

Computational and experimental probes of symmetry mismatches in the Arc repressor-DNA complex.Semantic proximity Read ↗

Defects in the calcium-binding region drastically affect the cadherin-like domains of RET tyrosine kinase.Semantic proximity Read ↗

Molecular dynamics simulations revealed structural differences among WRKY domain-DNA interaction in barley (Hordeum vulgare).Semantic proximity Read ↗

Correlated motions and interactions at the onset of the DNA-induced partial unfolding of Ets-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.