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Article

Association of HLA-G 3' UTR 14-bp insertion/deletion polymorphism with hepatocellular carcinoma susceptibility in a Chinese population.

DNA and cell biology - 1 Dec 2011

Jiang Yuting, Chen Shougong, Jia Shasha, Zhu Zhansheng, Gao Xueren, Dong Dong, Gao Yuzhen

Abstract excerpt

The 14-bp insertion/deletion (indel) polymorphism located in the 3' UTR of the human leukocyte antigen-G (HLA-G) gene plays a role in several autoimmune and chronic inflammatory diseases. HLA-G expression is associated with hepatocellular carcinoma (HCC) prognosis, especially in early stage, with high expression independently associated with shortened overall survival and increased tumor recurrence. In the...

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Identifiers

PMID: 21612396
DOI: 10.1089/dna.2011.1238

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