Article
Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells.
Journal of leukocyte biology - 1 Jul 2008
Anderson Amy E, Sayers Bethan L, Haniffa Muzlifah A, Swan David J, Diboll Julie, Wang Xiao-Nong, Isaacs John D, Hilkens Catharien M U
Abstract excerpt
Promising immunotherapeutic tools for T cell-mediated pathologies are alternatively activated dendritic cells (aaDC), which exert their effect through the regulation and tolerization of T cells. As naïve and memory T cells have different susceptibilities to tolerogenic signals, it is important to understand the modulatory effects of aaDC on these T cell subsets. We have examined regulation of naïve and memory...
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