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Article

Alternatively activated dendritic cells derived from systemic lupus erythematosus patients have tolerogenic phenotype and function.

Clinical immunology (Orlando, Fla.) - 1 Jan 2015

Wu Hai Jing, Lo Yi, Luk Daniel, Lau Chak Sing, Lu Liwei, Mok Mo Yin

Abstract excerpt

Tolerogenic dendritic cells (DCs) are potential cell-based therapy in autoimmune diseases. In this study, we generated alternatively activated DCs (aaDCs) by treating monocyte-derived DCs from patients with systemic lupus erythematosus (SLE) and healthy subjects with combination of 1,25 dihydroxyvitamin D(3) (vitD3) and dexamethasone followed by lipopolysaccharide-induced maturation. Lupus aaDCs were found to...

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Identifiers

PMID: 25463431
DOI: 10.1016/j.clim.2014.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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