Article
Glatiramer acetate treatment normalized the monocyte activation profile in MS patients to that of healthy controls.
Immunology and cell biology - 1 Mar 2017
Chuluundorj Delgertsetseg, Harding Scott A, Abernethy David, La Flamme Anne Camille
Abstract excerpt
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system, and monocytes contribute to MS-associated neuroinflammation. While classically activated monocytes promote inflammation, type II-activated monocytes improve the course of MS. This study investigated type II activation of monocytes and their two main subsets, namely CD14+ (CD14++CD16- subset) and CD16+ monocytes (CD14+CD16+...
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