Article
Functional phenotype of synovial monocytes modulating inflammatory T-cell responses in rheumatoid arthritis (RA).
PloS one - 1 Jan 2014
Yoon Bo Ruem, Yoo Su-Jin, Choi Yeon ho, Chung Yeon-Ho, Kim Jinhyun, Yoo In Seol, Kang Seong Wook, Lee Won-Woo
Abstract excerpt
Monocytes function as crucial innate effectors in the pathogenesis of chronic inflammatory diseases, including autoimmunity, as well as in the inflammatory response against infectious pathogens. Human monocytes are heterogeneous and can be classified into three distinct subsets based on CD14 and CD16 expression. Although accumulating evidence suggests distinct functions of monocyte subsets in inflammatory...
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