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Article

An Adaptive Fisher's Combination Method for Joint Analysis of Multiple Phenotypes in Association Studies.

Scientific reports - 3 Oct 2016

Liang Xiaoyu, Wang Zhenchuan, Sha Qiuying, Zhang Shuanglin

Abstract excerpt

Currently, the analyses of most genome-wide association studies (GWAS) have been performed on a single phenotype. There is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases. Therefore, using only one single phenotype may lose statistical power to identify the underlying genetic mechanism. There is an increasing need to develop and apply powerful statistical tests to detect...

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Identifiers

PMID: 27694844
DOI: 10.1038/srep34323
PMCID: PMC5046106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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