The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling.

doi:10.1182/blood-2016-05-714659

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Article

The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling.

Blood - 26 Jan 2017

Li Jin, Riedt Tamara, Goossens Steven, Carrillo García Carmen, Szczepanski Sabrina, Brandes Maria, Pieters Tim, Dobrosch Linne, Gütgemann Ines, Farla Natalie, Radaelli Enrico, Hulpiau Paco, Mallela Nikhil, Fröhlich Holger, La Starza Roberta, Matteucci Caterina, Chen Tong, Brossart Peter, Mecucci Cristina, Huylebroeck Danny, Haigh Jody J, Janzen Viktor

Abstract excerpt

Epithelial-to-mesenchymal-transition (EMT) is critical for normal embryogenesis and effective postnatal wound healing, but is also associated with cancer metastasis. SNAIL, ZEB, and TWIST families of transcription factors are key modulators of the EMT process, but their precise roles in adult hematopoietic development and homeostasis remain unclear. Here we report that genetic inactivation of Zeb2 results in...

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PMID: 27683414
DOI: 10.1182/blood-2016-05-714659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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