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Article

ZEB1-regulated inflammatory phenotype in breast cancer cells.

Molecular oncology - 1 Sept 2017

Katsura Akihiro, Tamura Yusuke, Hokari Satoshi, Harada Mayumi, Morikawa Masato, Sakurai Tsubasa, Takahashi Kei, Mizutani Anna, Nishida Jun, Yokoyama Yuichiro, Morishita Yasuyuki, Murakami Takashi, Ehata Shogo, Miyazono Kohei, Koinuma Daizo

Abstract excerpt

Zinc finger E-box binding protein 1 (ZEB1) and ZEB2 induce epithelial-mesenchymal transition (EMT) and enhance cancer progression. However, the global view of transcriptional regulation by ZEB1 and ZEB2 is yet to be elucidated. Here, we identified a ZEB1-regulated inflammatory phenotype in breast cancer cells using chromatin immunoprecipitation sequencing and RNA sequencing, followed by gene set enrichment...

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Chemokines
Culture Media, Conditioned
Mice, Nude
Myeloid Cells
Paracrine Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transforming Growth Factor beta

Zinc Finger E-box-Binding Homeobox 1

Zinc Finger E-box Binding Homeobox 2

Source

Open in PubMed Open full text

Identifiers

PMID: 28618162
DOI: 10.1002/1878-0261.12098
PMCID: PMC5579340

Genes

ZEB1
ZEB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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