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Article

Regulation of ZEB1 Function and Molecular Associations in Tumor Progression and Metastasis

7 Apr 2022

Abstract excerpt

Zinc finger E-box binding homeobox 1 (ZEB1) is a pleiotropic transcription factor frequently expressed in carcinomas. ZEB1 orchestrates the transcription of genes in the control of several key developmental processes and tumor metastasis via the epithelial-to-mesenchymal transition (EMT). The biological function of ZEB1 is regulated through pathways that influence its transcription and post-transcriptional...

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PMID: 35454770
DOI: 10.3390/cancers14081864

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