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Article

Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast.

Aging cell - 1 Aug 2013

Ballew Bari J, Lundblad Victoria

Abstract excerpt

Most human tissues express low levels of telomerase and undergo telomere shortening and eventual senescence; the resulting limitation on tissue renewal can lead to a wide range of age-dependent pathophysiologies. Increasing evidence indicates that the decline in cell division capacity in cells that lack telomerase can be influenced by numerous genetic factors. Here, we use telomerase-defective strains of budding...

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Identifiers

PMID: 23672410
DOI: 10.1111/acel.12099
PMCID: PMC3933227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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