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Article

Portrait of replication stress viewed from telomeres.

Cancer science - 1 Jul 2013

Ishikawa Fuyuki

Abstract excerpt

Genetic instability is the driving force of the malignant progression of cancer cells. Recently, replication stress has attracted much attention as a source of genetic instability that gives rise to an accumulation of mutations during the lifespan of individuals. However, the molecular details of the process are not fully understood. Here, recent progress in understanding how genetic alterations accumulate at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23557232
DOI: 10.1111/cas.12165
PMCID: PMC3881512

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