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Article

Generation of Full-Length Class I Human Leukocyte Antigen Gene Consensus Sequences for Novel Allele Characterization.

Clinical chemistry - 1 Dec 2016

Clark Peter M, Duke Jamie L, Ferriola Deborah, Bravo-Egana Valia, Vago Tunde, Hassan Aniqa, Papazoglou Anna, Monos Dimitri

Abstract excerpt

BACKGROUND: Routine, high-resolution human leukocyte antigen (HLA) genotyping by next generation sequencing within clinical immunogenetics laboratories can now provide the full-length gene sequence characterization of fully phased HLA alleles. This powerful technique provides insights into HLA variation beyond the traditionally characterized antigen recognition domain, providing sequence annotation across the...

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PMID: 27679434
DOI: 10.1373/clinchem.2016.260661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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