Article
Apolipoprotein E genotyping using PCR-GoldMag lateral flow assay and its clinical applications.
Molecular medicine reports - 1 Nov 2016
Lian Ting, Hui Wenli, Li Xianying, Zhang Chao, Zhu Juanli, Li Rui, Wan Yinsheng, Cui Yali
Abstract excerpt
A polymerase chain reaction-gold magnetic nanoparticles lateral flow assay (PCR-GoldMag LFA) has been developed via integrating multiplex amplification refractory mutation system PCR (multi‑ARMS‑PCR) with GoldMag‑based LFA for the visual detection of single‑nucleotide polymorphisms (SNPs). This assay was applied to genotype Apolipoprotein E (ApoE). ApoE genotyping is important due to the predictive value for the...
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