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Article

A novel lateral flow assay based on GoldMag nanoparticles and its clinical applications for genotyping of MTHFR C677T polymorphisms.

Nanoscale - 14 Feb 2016

Hui Wenli, Zhang Sinong, Zhang Chao, Wan Yinsheng, Zhu Juanli, Zhao Gang, Wu Songdi, Xi Dujuan, Zhang Qinlu, Li Ningning, Cui Yali

Abstract excerpt

Current techniques for single nucleotide polymorphism (SNP) detection require tedious experimental procedures and expensive and sophisticated instruments. In this study, a visual genotyping method has been successfully established via combining ARMS-PCR with gold magnetic nanoparticle (GoldMag)-based lateral flow assay (LFA) and applied to the genotyping of methylenetetrahydrofolate reductase (MTHFR) C677T. C677T...

Read the complete abstract on PubMed

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Share to Advanced biosensing and bioanalysis techniques
Share to MTHFR gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 26804455
DOI: 10.1039/c5nr07547e

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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