Article
BCR-ABL (Ph)-like acute leukemia-Pathogenesis, diagnosis and therapeutic options.
Blood reviews - 1 Mar 2017
Ofran Yishai, Izraeli Shai
Abstract excerpt
Recent comprehensive genetic studies revealed numerous genetic aberrations underlying a group of high-risk leukemias that share a specific activated kinase gene expression pattern. These ALLs were first recognized by the expression profile similar to that of Philadelphia chromosome-positive ALL and currently can be sub-classified by the main aberrantly activated kinase in the leukemic cells. We herein review the...
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