Article
[Research Progress on Pathogenic Genes of Ph-like Acute Lymphoblastic Leukemia--Review].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2020
Li Zeng-Zheng, Wang Ya-Jie, Feng Jia-Kun, Tan Jia-Bin, Zhao Ren-Bing, Yang Tong-Hua
Abstract excerpt
Abstract Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL or BCR-ABL1-like ALL) is a kind of acute leukemia which has the similar gene expression profiles and manifests the biological behavior same to Ph-positive ALL, but lacks the BCR-ABL1 fusion gene. Ph-like ALL was involved in multiple abnormal changes of genomes, activating kinase and cytokine receptor signaling. This review focuses on...
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