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Advances in the Genetics and Therapy of Acute Lymphoblastic Leukemia

2016-05-01

Abstract excerpt

Acute lymphoblastic leukemia (ALL) remains an important cause of morbidity in children and adults. In this article, we highlight advances in the genetics and therapy of three key subtypes of ALL: T-cell ALL, BCR-ABL1 (Philadelphia [Ph] chromosone–positive), and Ph-like ALL. T-ALL is an aggressive disease that accounts for about 15% and 25% of ALL among pediatric and adult cohorts, respectively, and exhibits a mult...

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Identifiers and source

Literature Corpus work
94865160-bbc5-5301-a715-c1b2b1fcf7d7
DOI
10.1200/edbk_156628
Open publication

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Advances in the Genetics and Therapy of Acute Lymphoblastic LeukemiaDOI 10.1200/edbk_156628
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