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Article

Mechanisms of hormonal regulation of the peripheral circadian clock in the colon.

Chronobiology international - 1 Jan 2017

Polidarová Lenka, Houdek Pavel, Sládek Martin, Novosadová Zuzana, Pácha Jiří, Sumová Alena

Abstract excerpt

Colonic function is controlled by an endogenous clock that allows the colon to optimize its function on the daytime basis. For the first time, this study provided evidence that the clock is synchronized by rhythmic hormonal signals. In rat colon, adrenalectomy decreased and repeated applications of dexamethasone selectively rescued circadian rhythm in the expression of the clock gene Per1. Dexamethasone entrained...

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Source

Identifiers

PMID: 27661138
DOI: 10.1080/07420528.2016.1231198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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