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Article

Low expression and hypermethylation of FOXP3 in regulatory T cells are associated with asthma in children

10 Jan 2020

Abstract excerpt

The aim of the present study was to determine the expression and methylation levels of forkhead transcription factor P3 (FOXP3) in peripheral blood CD4+CD25+ regulatory T cells (Tregs) harvested from children with asthma, and to explore the pathogenesis of asthma. The percentages of CD4+CD25+FOXP3+ Tregs in CD4+ T lymphocytes from 15 children with asthma and 15 healthy controls were measured by flow cytometry,...

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PMID: 32104264
DOI: 10.3892/etm.2020.8443

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